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NASA Spaceline Current Awareness List #1,160 1 August 2025 (Space Life Science Research Results)

NASA Spaceline Current Awareness List #1,160 1 August 2025 (Space Life Science Research Results)

The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

Matheson BE, Walle M, Liphardt A-M, Hulme PA, Heer M, Zwart SR, Sibonga JD, Smith SM, Gabel L, Boyd SK.Recovery of bone microarchitecture and density four years after spaceflight: Two case studies.npj Microgravity. 2025 Jul 28;11(1):47.Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 5.1

Funding: PIs report internal NASA funding. S.R. Zwart, J.D. Sibonga, and S.M. Smith are affiliated with NASA Johnson Space Center.

Darby EW, Armstrong SP, Massa GD, Walters KJ.Light intensity and photoperiod interact to alter the phytonutrient profile and light-use efficiency of mizuna grown for the space diet.Sci Rep. 2025 Jul 29;15:27573.PI: K.J. WaltersNote: This article may be obtained online without charge.

Journal Impact Factor: 3.9

Funding: “This work was funded by the NASA Space Biology Program grant 80NSSC22K0205.”

Thompson RS, Hopkins S, Kelley T, Wilson CG, Pecaut MJ, Fleshner M.A prebiotic diet containing galactooligosaccharides and polydextrose attenuates hypergravity-induced disruptions to the microbiome in female mice.Nutrients. 2025 Jul 24;17(15):2417.PI: M.J. PecautNote: This article is part of Special Issue “Advances in Gut Microbial Genomics and Metabolomics in Human Health” (https://www.mdpi.com/journal/nutrients/special_issues/53SG1V2YG1) and may be obtained online without charge.

Journal Impact Factor: 5.0

Funding: “This work was supported by NASA under the grant identification number: 80NSSC19K1038, 16-ROSBFP_PI-0079.”

Thomas D, Wu JC.Integrative approaches in cardiac tissue engineering: Bridging cellular complexity to create accurate physiological models.iScience. 2025 Aug 15;28(8):113003.PI: J.C. WuNote: This article may be obtained online without charge.

Journal Impact Factor: 4.1

Funding: “We thank Blake Wu for critical reading of the article and feedback. Manuscript figures were created with BioRender.com. This project was supported by grants from the National Institutes of Health R01 HL141851, R01 HL150693, R01 HL163680, UG3 TR005845, and U01 AI183953 (J.C.W.); K99 HL163443 (D.T.); Department of Energy DE-SC0025363 (J.C.W.); and National Aeronautics and Space Administration 80ARC022CA003 (J.C.W.).”

Bjurling J, Chavkin NW, Halvardson J, Thel MC, Mattisson J, Kim JS, Zaghlool A, Ma S-F, Martinez FJ, Anstrom K, Noth I, Walsh K, Forsberg LA.Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis.Commun Med. Jun 28;5:246.PI: K. WalshNote: This article may be obtained online without charge.

Journal Impact Factor: 6.3

Funding: “This study was supported by The European Research Council (101001789), The Swedish Research Council (2022-03452), The Swedish Cancer Society (23 2748 Pj 01 H), Konung Gustav V och Drottning Victorias Stiftelse, The Swedish Heart Lung Foundation (20230779) to L.A.F, National Institutes of Health (HL128964 and UG3HL145266) to I.N., American Heart Association (23CDA154358) to N.C.W., and National Aeronautics and Space Administration (80NSSC21K0549), National Heart, Lung and Blood Institute (HL152174) and National Institute on Aging (AG073249) to K.W.”

Shanghavi AA, Jayasuriya J, Cai Y, Mehta RK.Pulse rate variability from wearable wristwatches as a surrogate for heart rate variability? We think not yet.Proc Hum Factors Ergon Soc Annu Meet. 2025 Jul 9;10711813251357929.PI: R.K. MehtaNote: From the abstract: “This study assessed the reliability of pulse rate variability (PRV) from wrist worn photoplethysmography (PPG) as a substitute for heart rate variability (HRV) measured via electrocardiography (ECG), across tasks with varying loads and ambulation.”

Journal Impact Factor: 1.5

Funding: NASA grant #80NSSC24K0485 funding.

Tsang Y, Aryeh KS, Wang K, Himmelfarb J, Yeung CK, Kelly EJ.Enhancing therapeutic strategies and drug development for patients with kidney disease.Expert Opin Drug Saf. 2025 Jul 4;1-26. Review.PI: C.K. YeungNote: This article may be obtained online without charge.

Journal Impact Factor: 3.1

Funding: “Portions of this work were supported by the NASA contract 80ARC023CA001, the National Center for Advancing Translational Sciences (NCATS) [U2CTR004867, UH3TR000504, UG3TR002158], jointly by the NCATS and the Center for the Advancement of Science in Space (CASIS) [UG3TR002178], the National Institute of Environmental Health Sciences (NIEHS) [P30ES00703], Eunice Kennedy Shriver National Institute of Child Health and Human Development [R01HD102786], an unrestricted gift from Northwest Kidney Centers to the Kidney Research Institute, and the School of Pharmacy at the University of Washington (Ji-Ping Wang Award and Bradley Fellowship).”

Astrobiology, space biology, space life science, space medicine, Microgravity, ISS,

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