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NASA Spaceline Current Awareness List #1,172 31 October 2025 (Space Life Science Research Results)

NASA Spaceline Current Awareness List #1,172 31 October 2025 (Space Life Science Research Results)

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Ferraro S, Sengupta S, Shaw J, Dave A, Cheli M, Colon R, Zuccotti G, Mason CE, Marcovina S.Point of care testing of biochemical markers for monitoring astronauts during long duration missions in deep space.Clin Chem Lab Med. 2025 Oct 28. Online ahead of print.PI: C.E. MasonNote: From the abstract: “Investigations into human performance and health status during long-duration spaceflights are ongoing aboard the International Space Station (ISS) and are critical for planning missions beyond Low Earth Orbit (LEO). This review evaluates the current evidence on point-of-care-testing (POCT) in space, discussing requirements for POCT to support astronaut health during extended deep space missions and the potential for technology transfer to terrestrial healthcare.”

Journal Impact Factor: 3.7

Funding: “C.E.M. thanks the WorldQuant and GI Research Foundation, NASA (NNX14AH50G, NNX17AB26G, NNH18ZTT001N-FG2, 80NSSC22K0254, 80NSSC23K0832, 24-24NSCOR_2-0008, 24-24FLAG_2-0099 and 22-22SBR_2-0104), the National Institutes of Health (R01ES032638 and U54AG089334) and the LLS (MCL7001-18, LLS 9238-16, 7029-23).”

Seo D, Strickland HF, Zhou M, Barker R, Ferl RJ, Paul AL, Gilroy S.GLARE: Discovering hidden patterns in spaceflight transcriptome using representation learning.npj Microgravity. 2025 Oct 28;11:76.PI: S. GilroyNote: This article may be obtained online without charge.

Journal Impact Factor: 5.1

Funding: “The CARA experiment was supported by grant number GA-2013-104, Center for Advancement of Science in Space, to A.-L. Paul (PI) and R.J. Ferl (CoI). We gratefully acknowledge support from NASA 80NSSC19K0132, 80NSSC19K0126, and 80NSSC21K0577 to S.G.”

Landon LB, Begerowski SR, Roma PG, Whiting SE, Bell ST, Massa GD.Sustaining the Merry Space farmer with pick-and-eat crop production.npj Microgravity. 2025 Oct 27;11:72.Note: This article may be obtained online without charge.

Journal Impact Factor: 5.1

Funding: “This research was supported by the Human Health and Performance Contract NNJ15HK11B and NASA grant Master Task List #1075 (Principal Investigator: G.D. Massa).”

Litzenberg K, Basham R, Naing LY, Mathur P, Woldesellassie F, Landes S, Cowings P, Toscano W, Rashed H, Abell T.Nausea, autonomic function, and the astronauts: Concepts, findings, and applications to GIMD patient care.Dig Dis Sci. 2025 Oct 26. Online ahead of print.Note: This article may be obtained online without charge.

Journal Impact Factor: 2.5

Funding: P. Cowings and W. Toscano are affiliated with NASA Ames Research Center.

Orr C, Mackey E, Jamshidi-Parsian A, Byrum S, Pathak R, Griffin R, Reyna NS.Musculoskeletal miRNA profiling after exposure to simulated space stressors in mice.MicroPubl Biol. 2025 Oct 8:2025.Note: Hindlimb unloading study. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “Supported by NASA-EPSCoR 80NSSC21M0323 to Rupak Pathak.”

Peanlikhit T, Liu J, Ahmed T, Welsh JS, Karakach T, Shroyer KR, Whorton E, Rithidech KN.Daily consumption of apigenin prevents acute lymphoma/lymphoblastic leukemia in male C57BL/6J mice exposed to space-like radiation.Cancers. 2025 Oct 31;17(21):3513.PI: K.N. RithidechNote: This article is part of Special Issue “Radiation Exposure, Inflammation and Cancers” (https://www.mdpi.com/journal/cancers/special_issues/33Q81IUBU9). The Special Issue also includes articles from previous Current Awareness Lists #1,119 https://doi.org/10.3390/cancers16193392 and and #1,127 https://doi.org/10.3390/cancers16233954. This article may be obtained online without charge.

Journal Impact Factor: 4.4

Funding: “This research was supported by the National Aeronautics and Space Administration (NASA) Grant # 80NSSC19K0435, which was awarded to Rithidech. The APC was funded by the Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA.”

Wu V, DeMaio R, Jonsson A, Monteleone J, Flickinger K, Weissman A, Guyette F, Buysse D, Birabaharan J, Empey P, Callaway C.Examining the relationship between core temperature, heat balance, and energy expenditure.Ther Hypothermia Temp Manag. 2025 Oct 13. Online ahead of print.PI: K. Flickinger, C. CallawayJournal Impact Factor: 1.0

Funding: “This work was supported by the National Aeronautics and Space Administration (NASA) through a subaward to University of Pittsburgh (PI: Callaway) of grant NNX16AO69A to the Translational Research Institute for Space Health (TRISH) at Baylor College of Medicine.”

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