NASA Spaceline Current Awareness List #1,177 5 December 2025 (Space Life Science Research Results)

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The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

  • Pham J, Nandi SP, Balaian L, Engstrom C, Chang P, Mack K, van der Werf I, Klacking E, Sneifer J, Katragadda N, Wirtjes K, Ruiz A, Chilin-Fuentes D, Molina E, Mesci P, Stoudemire J, Morris SR, Whisenant T, Alexandrov LB, Jamieson CHM.Space-associated stem cell hallmarks of aging and resilience in astronauts.Cell Stem Cell. 2025 Dec 4;32(12): p1886-1903.e7.Note: ISS results. This article may be obtained online without charge.

    Journal Impact Factor: 20.4

    Funding: “We would like to acknowledge the significant contributions of the Axiom 2, Axiom 3, and Axiom 4 astronauts; Michelle Ortiguerra, MBA; and other members of the UC San Diego Sanford Stem Cell Institute (SSCI) and the Salk Institute NGS Core Facility. We are grateful to our funding agencies for their vital support, including NASA (NRA NNJ13ZBG001N), NCI (R01CA296974), NCI (R01CA205944), NIH/NIDDK (R01DK114468-01), NIH NCI CCSG p30CA023100, NIH NCI CCSG P30 CA01495, NIH NIA San Diego Nathan Shock Center (P30 AG068635), The Chapman Foundation and the Helmsley Charitable Trust, LLS Blood Cancer Discoveries, SSCI, the Koman Family Foundation, the JM Foundation, and the Moores Family Foundation.”

  • Tays GD, Fettrow TD, McGregor HR, Hupfeld KE, De Dios YE, Reuter-Lorenz PA, Bloomberg JJ, Mulavara AP, Wood SJ, Seidler RD.Sensory network segregation as a predictor of post spaceflight balance impairments and sensory re-weighting.npj Microgravity. 2025 Nov 27;11:85.PIs: H.R. McGregor, A.P. Mulavara, S.J. Wood, R.D. SeidlerNote: ISS results. This article may be obtained online without charge.

    Journal Impact Factor: 5.1

    Funding: “This work was supported by grants from the National Aeronautics and Space Administration (NASA 80NSSC18K0783) to R.S., A.M., S.W., and J.B. During the completion of this work G.T. was supported by the University of Florida’s (UF) Graduate Student Funding Award and by NIH T32-NS082128. K.H. was supported by National Institute on Aging fellowships (F99AG068440 and K00AG068440). H.M. was supported by a Natural Sciences and Engineering Research Council of Canada (NSERC) Postdoctoral Fellowship and a NASA Human Research Program Augmentation Grant. The authors would like to thank all the astronauts who volunteered their time, without them this project would not have been possible.”

  • Pitcher LE, Mukherjee B, Saathoff AM, Eduvas ZA, Bartz J, Zhang X, Giorgadze N, Pirtskhalava T, Habib AA, LeBrasseur NK, Tchkonia T, Kirkland JL, Dong X, Burma S, Robbins PD.Space radiation induces distinct senescent phenotypes: Implications for space travel.npj Aging. 2025 Nov 27;11:95.PI: S. BurmaNote: This article may be obtained online without charge.

    Journal Impact Factor: 6.0

    Funding: “Funding for this research was provided by grants from NASA 80NSSC20K0732 (SB) and NIH R01 CA246807 (SB), R01 AG069819 (PDR), P01 AG043376 (PDR), U19 AG056278 (PDR), P01 AG062413 (PDR, JLK, NKL), U54 AG079754 (PDR), U54 AG076041 (PDR), R37AG013925 (JLK), R33AG061456 (JLK) and T32AG029796 (LEP).”

  • Sevilla-García M, Quivira-Lopesino A, Cuesta P, Pusil S, Bruña R, Fiedler P, Maestu F, Cebolla AM, Cheron G, Brauns K, Stahn AC, Funke ME.Brain power comparison between microgravity and head-down tilt bedrest: An electroencephalography approach.Sci Rep. 2025 Nov 27;15:42314.PI: M.E. FunkeNote: This article may be obtained online without charge.

    Journal Impact Factor: 3.9

    Funding: “Presented EEG data analysis (M.S.G., A.Q.L., P.C., S.P., R.B., P.F., M.F., F.M.) is supported by the Translational Research Institute for Space Health (TRISH) through NASA Cooperative Agreement NNX16AO69A (Clinical trial number: not applicable). Obtaining the original EEG data, here used for comparison, from several ISS expeditions was funded by the Belgian Federal Science Police Office (A.C., G.C.), the European Space Agency (ESA), (AO-2004, 118 for A.C., G.C.; AO-2009-BR and AO-2013-BR for A.C.S), the Belgian National Funds for Scientific Research (G.C.), the research funds of the Université Libre de Bruxelles (A.C., G.C.), and the Université de Mons-Hainaut (G.C.). The HDBR data were obtained via research grant 50WB1525 (A.C.S.) supported by the European Space Agency and by the German Aerospace Center (DLR, Deutsches Zentrum für Luft- und Raumfahrt).”

  • Alexeev Y, Farag MH, Patti TL, Wolf ME, Ares N, Aspuru-Guzik A, Benjamin SC, Cai Z, Cao S, Chamberland C, Chandani Z, Fedele F, Hamamura I, Harrigan N, Kim JS, Kyoseva E, Lietz JG, Lubowe T, McCaskey A, Melko RG, Nakaji K, Peruzzo A, Rao P, Schmitt B, Stanwyck S, Tubman NM, Wang H, Costa T.Artificial intelligence for quantum computing.Nat Commun. 2025 Dec 2;16:10829. Review.Journal Impact Factor: 15.7

    Funding: N.M. Tubman is affiliated with NASA Ames Research Center.

  • astrobiology, Microgravity, space biology, space medicine, space station, spaceline,

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