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NASA Spaceline Current Awareness List #1,181 31 December 2025 (Space Life Science Research Results)

NASA Spaceline Current Awareness List #1,181 31 December 2025 (Space Life Science Research Results)

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Kumar K, Angdisen J, Fornace AJ Jr, Suman S.Elevated SASP factors, reduced antioxidant enzymes, and increased tumor susceptibility in space radiation-exposed Apc^Min/+ mice.Int J Mol Sci. 2025 Dec 24;27(1):211PIs: A.J. Fornace Jr, S. SumanNote: This article is part of Section “Molecular Biology” (https://www.mdpi.com/journal/ijms/sections/Molecular_Biology) and may be obtained online without charge.

Journal Impact Factor: 4.9

Funding: “This research was funded by the National Aeronautics and Space Administration (NASA), grant number 80NSSC22K1279 (PI: Albert J. Fornace, Jr.), and 80NSSC24K0287 (PI: Shubhankar Suman). We acknowledge the Lombardi Comprehensive Cancer Shared Resources, which is supported by NCI grant number P30CA051008 (PI: Louis Weiner).”

Meas SJ, Daire GM, Buettmann EG, Donahue HJ.Hindlimb unloading results in accelerated bone loss compared to aging in select bone compartments of female murine femurs.J. Biomech. 2026 Jan;195:113134.PI: E.G. Buettmann, H.J. DonahueNote: This article may be obtained online without charge.

Journal Impact Factor: 2.4

Funding: “This work was funded by NIH R01 AR068132, NASA 80NSSC18K1473, and CIHR DFSA 454761. Services and products in support of the research project were generated by the Virginia Commonwealth University Tissue and Data Acquisition and Analysis Core Laboratory, supported, in part, with funding to the Massey Cancer Center from NIH-NCI Cancer Center Support Grant P30 CA016059. Dr. Buettmann was funded via by the Translational Research Institute for Space Health (TRISH)through Cooperative Agreement with NASA (NNX16AO69A) and NIAMS NIH NIAMS (Grant K99AR082989).”

Mohajeri M, Wang T-C, Agarwal P, Kaur S, Kumar A, Dickinson RB, Jain A, Lele TP.Evidence for drop-like nuclear deformation in sheared endothelial monolayers.Small. 2025 Dec 26;e06536.PI: A. JainNote: This article may be obtained online without charge.

Journal Impact Factor: 12.1

Funding: “This work was supported by the National Institutes of Health grant U01CA225566 (to T.P.L. and R.B.D.), the Cancer Prevention and ResearchInstitute of Texas Established investigator award RR200043 (to T.P.L.),the National Science Foundation awards 2412520 and 2226157 (to T.P.L.),and 2226156 to R.B.D, the US Army Medical Research (USAMRAA)Contract No. HT94252410432; NASA, BARDA, NIH, and USFDA, underContract No. 80ARC023CA002; and NHLBI of NIH under Award NumberR01HL157790 (to A.J.).”

Sheik CS, Steen AD, Reese BK, Wang DT, Osburn MR, Cantner KA, Kieft TL, Colwell FS, Spear JR, Toner BM.Subsurface microbiology and the pressing societal need to support future exploration.FEMS Microbiol Ecol. 2025 Dec 22;102(1):fiaf121. Review.Note: This article may be obtained online without charge.

Journal Impact Factor: 3.2

Funding: “NSF OCE-2145434 funded A.D.S., NSF EAR-1813526 funded C.S.S. and B.M.T., and NSF EAR-2026858 funded T.L.K. NASA PICASSO23- 0026 funds J.R.S.”

Stepanyan A, Hakobyan S, Brojakowska A, Bisserier M, Zakharyan R, Davitavyan S, Sirunyan T, Khachatryan G, Khlgatian MK, Zhang S, Baghoomian A, Sahoo S, Hadri L, Garikipati VNS, Arakelyan A, Goukassian DA.Long-term impact of Western diet on right ventricular transcriptome: Uncovering sex-specific patterns in C57BL/6J mice.Int J Mol Sci. 2025 Dec 26;27(1):259.PI: D.A. GoukassianNote: This article is part of Section “Bioactives and Nutraceuticals” (https://www.mdpi.com/journal/ijms/sections/bioactives) and may be obtained online without charge.

Journal Impact Factor: 4.9

Funding: “This work was funded by the NASA Human Research Program, grant No: 80NSSC19K1079 (formerly, 80NSSC18K0921) and grant No: 80NSSC21K0549 (PI-Kenneth Walsh, DAG-subcontract) to D.A.G., the American Heart Association Career Development Award (24CDA1269532 to MB), and the ADVANCE Research Grant provided by the Foundation for Armenian Science and Technology and Research Grants 25FAST-1F004 and 24RL-1F029 funded by the Higher Education and Science Committee of the Ministry of Education, Science, Culture and Sport of the Republic of Armenia.”

Ma S, Dolde J, Zheng X, Ganapathy D, Shtov A, Chen J, Stöltzel A, Christensen BJ, Kolkowitz S.Enhancing optical lattice clock coherence times with erasure conversion.PRX Quantum. 2025 Nov 19;6(4):040340.PI: S. KolkowitzNote: This article may be obtained online without charge.

Journal Impact Factor: 11.0

Funding: “This work was supported by a Packard Fellowship for Science and Engineering, the Army Research Office through Agreement No. W911NF-21-1-0012, the Sloan Foundation, the Simons Foundation, the John Templeton Foundation, the Gordon and Betty Moore Foundation under Grant DOI 10.37807/gbmf12966, NASA under Grant No. 80NSSC24K1561, and the National Science Foundation under Grants No. 2143870 and No. 2326810.”

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